

Brainiac has also freed Gorilla Grodd from imprisonment, who intends to take revenge on his jailors and humanity with use of his Earthquake Machine. Superman and J'onn J'onnz travel to Mars to stop them from escaping but this has been yet another diversion from Brainiac who, anticipating their success, took the opportunity to steal vital equipment from the White Martians. However, the League realize it has been upgraded capable of breaking Earth's orbit, the missile has actually been fired at Mars in an effort to free the White Martians, who will invade Earth upon being rewoken. Despite the League's efforts, one missile is launched undetected during a worldwide communications blackout caused by Brainiac. After Metropolis has been saved, the League responds to a series of attempted nuclear missile hijackings firstly, The Key attempts to hijack a missile before he is subdued by the Flash and Green Lantern ( John Stewart), followed by an attempt by Killer Frost which is foiled by Zatanna and Wonder Woman. Meanwhile, Zatanna and J'onn Jonzz (the Martian Manhunter) face off against Queen Bee and her drones, who are being assisted in their gradual conversion of Metropolis by some of Brainiac's robots. After the two superheroes defeat what they think is Brainiac, they discover that they have merely been diverted by a duplicate whilst another has raided the vaults of the Lab, taking Kryptonian DNA and a chunk of meteorite. The game starts with Batman and Superman foiling an attack on S.T.A.R. This version was developed by WayForward Technologies. The game featured 2D sidescrolling action gameplay (similar to 16-bit era games) and a sidestory to the console game's plot.

The GBA version is titled Justice League Heroes: The Flash and focused primarily on The Flash. This version was developed by Sensory Sweep Studios.

The Nintendo DS game shares a similar visual style and gameplay mechanics to the console game, but serves as a prequel to its story. Two handheld Justice League Heroes games were released at the same time for the GBA and Nintendo DS systems. Games and Eidos Interactive in conjunction with DC Comics. It was developed by Snowblind Studios and published by Warner Bros. It is based on DC Comics' premiere superhero team, the Justice League of America. Justice League Heroes is a console video game for the Xbox, PlayStation 2, Nintendo DS, and PlayStation Portable systems.
